Figure 1: Infant gut microbiota community profiles during the first month of life.

(a) Microbiota profiles in stool samples from 12 subjects (n=202; ∼17 sampling days per subject), temporally ordered from left to right. Each row represents taxonomic groups at the family level. The top 15 families are displayed and sorted according to relative abundance. Abundances are represented using the colour scale. (b) Characteristics of infant gut microbiota, illustrated by PCoA and PAM clustering analyses. Data from individuals (points) were clustered, and the centres of gravity (rectangles) were computed for each class. The coloured ellipses encompass 67% of the samples in each cluster. (c) Box plots showing the relative abundances of the main contributors to each cluster. Different letters (a–c) above the boxes indicate significant differences between clusters (P<0.05, Mann–Whitney U-test with Bonferroni’s correction). (d) Temporal shift from Staphylococcaceae- or Enterobacteriaceae-dominant microbiota to Bifidobacteriaceae-dominant microbiota. S, Staphylococcaceae-dominated (yellow); E, Enterobacteriaceae-dominated (blue); B, Bifidobacteriaceae-dominated (red); NT, not tested; —, sample not provided.