Figure 1: Manhattan plot of association P-values.
From: Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
Shown are the genome-wide P-values (two sided) of 12.4 million successfully imputed autosomal SNPs in 7,319 cases and 234,385 controls from the discovery phase. Labelled in blue are previously identified risk loci and labelled in red are newly identified risk loci. The red horizontal line represents the genome-wide significance threshold of P=5.0 × 10−8 and the blue horizontal line represents the threshold of P=1.0 × 10−6 used to define promising SNPs.
