Figure 2: Structural analysis of MapZ_extra.

(a) Cartoon representation of the NMR ensemble of the 20 lowest-energy structures of MapZ_extra1 (lower structure) and MapZ_extra2 (upper structure). The ensemble on the right is rotated by 180° along the y axis compared with the structures on the left. The serine-rich linker (SRL) is pictured as a grey curved line. N- and C-terminal residues as well as α-helices are annotated. (b) Topology of the MapZ_extra2 subdomain. α-Helices and β-strands are represented by grey circles and arrows, respectively. (c) Topology of the MapZ_extra1 subdomain. Similarly to b, α-helices are shown as grey circles. The most significant residues that are implicated in hydrophobic interactions and maintain the global structure are displayed as white circles, while hydrophobic contacts are emphasized as dotted lines. In b and c, residues delimiting the loops pictured as black lines are indicated.