Figure 5: The molecular mechanism of pironetin and other tubulin-targeting agents to alter the tubulin-microtubule dynamics.
From: Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubule
The tubulin-targeting agents colchicine, vinblastine and taxol are shown. This figure is inspired by a previous publication10 but designed and developed with the data in this study.
