Figure 6: Postsynaptic Fur1 is required for enhancement of synaptic transmission by dLRRK.
From: LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction
(a) Quantification of mEJC, EJC and QC from control (MHC-Gal4/+), dLRRK OE (UAS-dLRRK/+; MHC-Gal4/+) and dLRRK OE Fur1/+ (UAS-dLRRK/+; MHC-Gal4/Fur1rl205). n=10, 10 and 10. (b) Representative traces for mEJC and EJC in control (MHC-Gal4/+), dLRRK and eGFP co-expression in muscle (+/UAS-dLRRK; MHC-Gal4/UAS-eGFP) and dLRRK muscle overexpression with Fur1 RNAi (+/UAS-dLRRK; MHC-Gal4/UAS-Fur1-RNAi). (c) Quantification of mEJC, EJC and QC from the genotypes shown in a. n=18, 18 and 18. Error bars represent s.e.m. *P<0.05, **P<0.01 and ***P<0.001. See also Supplementary Table 1.
