Figure 2: Genes delineate neurons with distinct connectivities.
From: Molecular signatures of neural connectivity in the olfactory cortex
(a) Cux1 marks OB-projecting neurons. CTB-labelled cells are shown in green, immunohistochemistry for Cux1 or Reelin in red. Insert: a CTB+/Cux1+ cell at high magnification. Fraction of CTB-labelled cells expressing Cux1: 80±6%. OB-projecting neurons are Reelin−. Scale bar, 100 μm. (b) Reelin marks CoA-projecting neurons. Insert: a CTB+/Reelin+ cell at high magnification. Fraction of CTB-labelled cells expressing Reelin: 83±6%. CoA-projecting neurons are Cux1−. (c) Reelin also marks lENT-projecting neurons. Insert: a CTB+/Reelin+ cell at high magnification. Fraction of CTB-labelled cells expressing Reelin: 90±4%. lENT-projecting neurons are Cux1−. Fractions of co-labelled cells are mean±s.e.m. (see main text for details). Schemes represent the laminar distribution and the molecular identities of neurons with distinct connectivities.
