Figure 3: EFIL-containing isPFKFB3KD mechanisms have reduced filopodia. | Nature Communications

Figure 3: EFIL-containing isPFKFB3KD mechanisms have reduced filopodia.

From: Glycolytic regulation of cell rearrangement in angiogenesis

Figure 3

(a-n) Number and length of filopodia for in silico WT (isWT) and in silico PFKFB3KD (isPFKFB3KD) cells, modelled by modifying the single mechanisms EFIL (a,b), ECOR (c,d) and EADH (e,f), and the combinatorial mechanisms EFIL/COR (g,h), EFIL/ADH (i,j), ECOR/ADH (k,l) and EALL (m,n). Data are mean±s.e.m.; n=4–5; NS, not significant, *P<0.05, **P<0.01, ***P<0.001; Student’s t-test.

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