Table 4 The endoplasmic reticulum (ER) stress response-related molecules with significantly altered expression.
From: Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis
Gene symbol | Object type | Description | Integrity biomarker | Signal (fold change) | P value |
|---|---|---|---|---|---|
DDIT3 | Transcription factor | DNA damage-inducible transcript 3 protein | DNA damage-inducible transcript 3 | 7.711006 | 1.05E−04 |
HERPUD1 | Generic binding protein | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein | 6.36406 | 1.37E−04 |
PPP1R15A | Generic binding protein | Protein phosphatase 1 regulatory subunit 15A | Protein phosphatase 1 regulatory subunit 15A | 4.787228 | 2.70E−04 |
HSPA5 | Generic binding protein | 78 kDa glucose-regulated protein | Heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa) | 3.58693 | 4.49E−04 |
EDEM1 | Generic enzyme | ER degradation-enhancing alpha-mannosidase-like protein 1 | ER degradation-enhancing alpha-mannosidase-like 1 | 2.713944 | 1.09E−03 |
XBP1 | Transcription factor | X-box-binding protein 1 | X-box-binding protein 1 | 2.443152 | 9.49E−05 |
HSP90B1 | Generic binding protein | Endoplasmin | Endoplasmin | 2.367735 | 2.89E−04 |
NFKBIA | Generic binding protein | – | Nuclear factor of kappa light polypeptide gene enhancer in B-cell inhibitor, alpha | 2.134665 | 4.07E−04 |
ATF-4 | Transcription factor | Cyclic AMP-dependent transcription factor ATF-4 | Cyclic AMP-dependent transcription factor ATF-4 | 2.045582 | 7.35E−04 |
