Figure 1: Ectopic expression of miR-625-3p is associated with increased viability in oxPt medium. | Nature Communications

Figure 1: Ectopic expression of miR-625-3p is associated with increased viability in oxPt medium.

From: miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells

Figure 1

(a) Cell proliferation upon DOX induction of miR-625-3p in the CRC cell lines HCT116.625, SW620.625 and control cells expressing a scrambled shRNA was determined by an MTT assay after 72 h of growth. Displayed as mean±s.e.m. (n=3). (b) Cell proliferation after 48 h of oxPt treatment was assessed by MTT in DOX-induced HCT116.625, SW620.625. Displayed relative to untreated cells as mean±s.e.m. (n=3). (c) IC50 values were calculated on the basis of experiments from b as well as from wild-type cells not subjected to pSBInducer transposition. Displayed as mean IC50±s.e.m. (n=3). *P≤0.05 (t-test); NS, not significant.

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