Table 1 Study on the dormant period monitored by means of in situ FT-IR analysis.

From: Asymmetric counteranion-directed Lewis acid organocatalysis for the scalable cyanosilylation of aldehydes

Entry

Initial dormant period (min)

Water added (mol%)

Induced dormant period (min)

1

110

0

0

2

118

1

17

3

109

5

80

4

109

10

170

  1. Conditions of step A (Fig. 5): aldehyde 2a (0.10 mmol), TMSCN 3 (2.0 equiv.) and catalyst 1a (2 mol%) in Et2O (5.0 ml) at 25 °C. Water (1–10 mol%) was added at the marked time point step B (Fig. 5).
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