Figure 5: miR-183/96/182 modulation in the hippocampus affects long-term object memory. | Nature Communications

Figure 5: miR-183/96/182 modulation in the hippocampus affects long-term object memory.

From: The microRNA cluster miR-183/96/182 contributes to long-term memory in a protein phosphatase 1-dependent manner

Figure 5

(a) Experimental setup. (b) Object discrimination ratio (expressed as per cent of controls) in miR-183/96/182 overexpressing mice and controls during memory test 24 h (Test 1, t32=0.298, P=0.77) and 48 h (Test 2, t32=2.65, *P<0.05) after acquisition; controls, n=19; miR-183/96/182, n=15. (c) Object discrimination ratio (expressed as per cent of controls) in miR-183/96/182 sponge expressing mice and controls during memory test at 24 h (Test 1, t18=2.18, *P<0.05) and 48 h (Test 2, t16=1.079, P=0.297); controls, n=9–10, miR-183/96/182 sponge, n=10–11. Bar graphs represent mean±s.e.m.

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