Figure 7: Effect of miR-182/HDAC9 TSB on NOR performance in mice overexpressing miR-183/96/182. | Nature Communications

Figure 7: Effect of miR-182/HDAC9 TSB on NOR performance in mice overexpressing miR-183/96/182.

From: The microRNA cluster miR-183/96/182 contributes to long-term memory in a protein phosphatase 1-dependent manner

Figure 7

(a–c) Behavioural measures during acquisition: total distance covered (a, t15=0.333, P=0.74); total time spent in center (b, t15=0.481, P=0.64); and total time spent exploring the objects (c, t15=2.12, *P<0.05). (d) Left panel: total time spent exploring objects during Test 1 (t15=1.90, #P<0.1). Right panel: discrimination ratio of novel versus familiar objects during Test 1 (t15=0.343, P=0.74). (e) Left panel: total time spent exploring objects during Test 2 (t15=1.22, P=0.24). Right panel: discrimination ratio of novel versus familiar objects during Test 2 (t15=1.04, P=0.32). Controls, n=9; miR-182/HDAC9 TSB, n=8. Bar graphs represent mean±s.e.m; red broken line indicates chance level of performance.

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