Figure 3: CES signature is prognostic for cancer patient overall survival. | Nature Communications

Figure 3: CES signature is prognostic for cancer patient overall survival.

From: Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy

Figure 3

(a–f) Kaplan–Meier survival estimations for individual breast cancer and lung cancer data sets for overall survival (OS). Each cohort was divided into CES high (red), intermediate (blue) and low (green) tertiles. Sample sizes and log-rank P values are indicated. (g) Forest plot summarizing prognostic impact of CES on patient OS by multivariate Cox regression using individual data sets. Squares and error bars in the plots denote log2 scales of hazard ratio (HR) and 95% confidence interval (CI), respectively. See details for multivariate Cox regression analysis for each data set in Supplementary Tables 15–25. Breast cancer NKI data set, lung ADC GSE31210 data set and NSCLC UT SPORE GSE42127 subcohort contain only stage I and II samples.

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