Figure 4: Ionotropic glutamate receptors are necessary for BC wave occurrence.
From: Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors
(a,c) Effects of APV (top, 100 μM) and CNQX (bottom, 50 μM) bath application on spontaneous calcium waves (a) or GDPs (c) of BCs in 3-d.p.f. larvae. (b,d) Summary of calcium imaging (b) and whole-cell recording data (d). The number in the brackets represents the number of retinae imaged (b) or BCs recorded (d). *P<0.05, **P<0.01, ***P<0.001; two-tailed paired Student’s t-test for the data between control and drug treatment, and two-tailed unpaired Student’s t-test for the data between APV and CNQX. Data are represented as mean±s.e.m.
