Figure 2: Scanning electron microscopic and vascular cast analyses of liver microvasculatures. | Nature Communications

Figure 2: Scanning electron microscopic and vascular cast analyses of liver microvasculatures.

From: Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism

Figure 2

(a,b) Representative scanning electron microscopy and vascular cast micrographs of liver microvessels of various groups. Red arrowheads point to enlarged open pores of the liver sinusoidal endothelium. Yellow arrowheads indicate bulb-like leaky structures of liver microvessels. Scale bar in upper panels, 200 nm. Scale bar in lower panels, 50 μm. (c,d) Quantifications of numbers large open pores above 200 nm in diameters. Data were quantified from 10 random fields per group. (e,f) Quantifications of numbers bulb-like leaky structures. Data were quantified from 10 random fields per group. OFF, off-drug; ON, on-drug. (mean±s.e.m., NS, not significant, Student’s t-test).

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