Figure 2: Mcp1 deletion in nestin+ cells delays atherosclerosis progression.
From: Nestin+ cells direct inflammatory cell migration in atherosclerosis
(a,c) Representative photographs of whole-mounted aortas from tamoxifen-treated (a) Cdh5-creERT2;Mcp1f/f;ApoE−/− mice, (c) Nes-creERT2;Mcp1f/f;ApoE−/− mice and control littermates (without Cre) two months after HFD, stained with Oil Red O (red) to mark atheroma plaques (n=6). (a,c) Scale bar, 1 mm. (b,d) Lesion size and coverage in the aortic arch (left) and number of lesions in the thoracic aorta (right) of these mice (n=3–6). Data are means±s.e.m.; n and P values are indicated; *P<0.05, unpaired two-tailed t test.
