Figure 6: Zdhhc21dep/dep mice are resistant to SIRS-induced lung injury and mortality.

(a,b) Representative images of lung tissues obtained from mice 24 h after thermal injury-induced (a) or LPS-induced SIRS (b) (five mice in each group). Scale bar, 50 μm. (c) Lung histology injury scores in thermal injury-induced SIRS. Results represent mean±s.e.m. from five mice. **P<0.01. (d) Survival rates in mice subjected to thermal injury (n=15 mice). (e) Lung histology injury scores in LPS-induced SIRS. Results represent mean±s.e.m. from five mice. **P<0.01, ***P<0.001. (f) Survival rates in mice subjected to LPS challenge (n=10 mice).