Figure 2: Extreme ASE genes preferentially identified in WGS subjects.
From: Loss of RNA expression and allele-specific expression associated with congenital heart disease
Shown in a are the number of genes with a minimum expression of 2 r.p.m. (grey bars), and the number of expressed genes that contain heterozygous SNPs (black bars) for CHD WGS (n=30 tissues) and CHD WES probands (n=142 tissues), GTEx donors (n=113 tissues) and mouse C57Bl6/Castaneus F1 hybrids (n=7 tissues). s.d. is indicated. b The distribution of extreme ASE events per subject by genotyping platform. Extreme ASE events were identified in >70% of WGS subjects (n=14). However, extreme ASE events were identified in only ∼20% of WES subjects (n=130) and ∼45% of GTEx donors (n=95).
