Figure 3: Broad nAb responses against 10-valent and 25-valent inactivated HRV in mice.
From: A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques
The inactivated-TCID50 input titres per dose are specified in Supplementary Table 2. (a) 20 mice were vaccinated then boosted at 50 days with 10-valent HRV. (b) 30 mice were vaccinated then boosted at 50 days with 25-valent HRV. Sera were collected at day 18 (prime) and day 68 (boost). nAb levels against the indicated types in the vaccines were measured in pooled sera. Error bars depict 95% confidence interval. Data shown represent one of three (10-valent) or two (25-valent) experiments with similar results. The dashed line represents LOD. Undetectable nAb were assigned LOD/2.
