Figure 5: Distributions of the ranks of matched perturbations between signatures from CREEDS and the LINCS L1000 dataset.
From: Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd
The highest ranks (a,c), and all ranks (b,d) of matched drugs (a,b) and matched genes (c,d) are presented. Drug perturbation signatures from CREEDS were queried against ∼30,000 significant drug perturbation signatures from the LINCS L1000 dataset; whereas gene perturbation signatures from CREEDS were queried against ∼110,000 gene perturbation signatures from the LINCS L1000 dataset.
