Table 1 Top hits for drug signatures extracted from GEO queried against drug perturbations from the LINCS L1000 dataset processed using the Characteristic Direction method.
From: Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd
Drug name | PubChem ID | GEO Accession | organism | GEO platform | Rank |
|---|---|---|---|---|---|
Dexamethasone | 5743 | GSE34313 | human | GPL6480 | 1 |
Doxorubicin | 31703 | GSE58074 | human | GPL10558 | 1 |
Azacitidine | 9444 | GSE29077 | human | GPL571 | 1 |
Azacitidine | 9444 | GSE29077 | human | GPL571 | 1 |
Azacitidine | 9444 | GSE29077 | human | GPL571 | 1 |
Lapatinib | 208908 | GSE38376 | human | GPL6947 | 2 |
Methylprednisolone | 6741 | GSE490 | rat | GPL85 | 2 |
Lapatinib | 208908 | GSE38376 | human | GPL6947 | 2 |
Dexamethasone | 5743 | GSE54608 | human | GPL10558 | 3 |
Lapatinib | 208908 | GSE38376 | human | GPL6947 | 3 |
Tretinoin | 444795 | GSE1588 | mouse | GPL81 | 3 |
Methylprednisolone | 6741 | GSE490 | rat | GPL85 | 3 |
Tretinoin | 444795 | GSE32161 | human | GPL570 | 3 |
Methylprednisolone | 6741 | GSE490 | rat | GPL85 | 3 |
Methylprednisolone | 6741 | GSE490 | rat | GPL85 | 4 |
Trichostatin A | 444732 | GSE1437 | mouse | GPL81 | 4 |
Dexamethasone | 5743 | GSE7683 | mouse | GPL1261 | 5 |
Cycloheximide | 6197 | GSE8597 | human | GPL570 | 5 |
Methylprednisolone | 6741 | GSE490 | rat | GPL85 | 6 |
Sorafenib | 216239 | GSE39192 | human | GPL6947 | 7 |
Vemurafenib | 42611257 | GSE37441 | human | GPL10558 | 8 |
Methylprednisolone | 6741 | GSE490 | rat | GPL85 | 10 |
Curcumin | 969516 | GSE10896 | human | GPL570 | 14 |
Curcumin | 969516 | GSE10896 | human | GPL570 | 15 |
Vemurafenib | 42611257 | GSE37441 | human | GPL10558 | 15 |
Lapatinib | 208908 | GSE38376 | human | GPL6947 | 16 |
Methylprednisolone | 6741 | GSE490 | rat | GPL85 | 17 |
Tretinoin | 444795 | GSE1588 | mouse | GPL81 | 20 |
Vemurafenib | 42611257 | GSE42872 | human | GPL6244 | 23 |
Azacitidine | 9444 | GSE29077 | human | GPL571 | 24 |
Troglitazone | 5591 | GSE21329 | rat | GPL341 | 31 |
Decitabine | 451668 | GSE29077 | human | GPL571 | 36 |
Vemurafenib | 42611257 | GSE37441 | human | GPL10558 | 36 |
Thapsigargin | 446378 | GSE19519 | human | GPL570 | 37 |
Methylprednisolone | 6741 | GSE490 | rat | GPL85 | 48 |
