Table 2 Top enriched human phenotypes of putative target genes near predicted heart enhancers.

From: Genome-wide compendium and functional assessment of in vivo heart enhancers

Top enriched phenotypes

Binomial FDR Q-value

Binomial fold enrichment

Cardiac arrest

6.81 × 10−89

2.0

Sudden cardiac death

7.84 × 10−89

2.0

Sudden death

3.67 × 10−84

3.1

Syncope

1.22 × 10−64

2.2

Atrial fibrillation

8.88 × 10−62

2.0

Abnormal EKG

4.89 × 10−44

2.0

Ventricular tachycardia

6.28 × 10−44

2.6

Aortic dissection

9.09 × 10−43

2.2

Bicuspid aortic valve

1.60 × 10−39

2.2

Pointed chin

9.10 × 10−35

2.0

Aortic aneurysm

1.13 × 10−34

2.3

Prolonged QT interval

3.91 × 10−34

2.2

  1. EKG, electrocardiogram; FDR, false discovery rate corrected. Additional highly enriched terms are included in Supplementary Table 3.
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