Figure 5: H2A.Z modulates the mobility of nucleosomes.
From: H2A.Z controls the stability and mobility of nucleosomes to regulate expression of the LH genes
(a) Experimental scheme for repetitive disruption of region 1. (b) Typical results for the repetitive disruption of the first interaction region in 601 nucleosomes containing H2A (left) and H2A.Z (right). (c) Positional dispersion for H2A- and H2A.Z-containing nucleosomes, reconstituted on 601 DNA, calculated as the standard dispersion over time, for the repetitive probing of an individual nucleosome. Data shown are the mean s.d.±s.e.m., nnucleosomes=5 and 4; nrepetitions=5–36; P=0.007, Kolmogorov–Smirnov test. **P<0.01. (d) Positional dispersion calculated as the standard dispersion in the position of the ensemble of Fig. 4d±s.e., n=28 and 27; P=9 × 10−5, two-sample Ansari–Bradley test. ***P<0.001.
