Figure 1: Aromatic thiol-mediated one-pot traceless native chemical ubiquitylation.
From: Aromatic thiol-mediated cleavage of N–O bonds enables chemical ubiquitylation of folded proteins

MPAA, 4-mercaptophenylacetic acid; UbΔG76-SR, ubiquitin(1–75)-α-thioester with 2-mercaptoethanesulfonic acid. PDB code 1UBQ (ubiquitin).