Figure 7: Material transfer involves interaction between donor and host photoreceptors | Nature Communications

Figure 7: Material transfer involves interaction between donor and host photoreceptors

From: Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors

Figure 7

NrlGFP+/CD73+ (green) and DsRed+/CD73+ (red) donor cells were transplanted into adult wild-type and Gnat1−/− recipients. (a–c), confocal projection images showing heterogeneous mixes of DsRed+ (closed arrow) and GFP+ (open arrow) cells within the host ONL. Occasionally, a photoreceptor within the host ONL bore both GFP and DsRed labels (asterisk). Nuclei are labelled with Hoechst (blue). (d,e), confocal projection images showing a similar finding for donor cells in the SRS. The majority expressed either GFP (open arrow) or DsRed (closed arrow), but some expressed both reporters (asterisk). For all panels, images from left to right show individual and/or combined channels for the same region of interest. Scale bars 10 μm.

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