Figure 8: Schematic summary of the pathways regulated by Prox1 in mature skeletal muscle fibres and satellite cells. | Nature Communications

Figure 8: Schematic summary of the pathways regulated by Prox1 in mature skeletal muscle fibres and satellite cells.

From: The transcription factor Prox1 is essential for satellite cell differentiation and muscle fibre-type regulation

Figure 8

Prox1 is expressed in mature slow muscle fibres, where it regulates NFAT signalling and muscle fibre type gene programs. Prox1 is also expressed in satellite cells, where it interacts with Notch signalling pathway, and it is essential for myoblast differentiation.

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