Figure 2: Structures of the nucleotide-free V1 (eV1) and 2AMP-PNP-bound V1 complexes (bV1 and 2ATPV1).
From: Crystal structures of the ATP-binding and ADP-release dwells of the V1 rotary motor
(a) Side view of eV1. (b) Top view of the C-terminal domain (transparent surface in a) from the cytoplasmic side. Open (O and O'; light), closed (C; dark) and closer (CR; darker) conformations of Eh-A and Eh-B are shown. Red arrows indicate the nucleotide-binding sites. (c,e) Side views of bV1 (c) and 2ATPV1 (e). (d,f) Top views of bV1 (d) and 2ATPV1 (f) as shown in b, which are superimposed at the ‘bound’ form onto that of eV1 (grey). The bound AMP-PNP molecules are shown in space-filling representation, coloured in red.
