Table 2 Biomarker staging of AD pathology in the HC and MCI-NP groups.
From: Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
Subgroups | |||
---|---|---|---|
HC Aβ+ | MCI-NP Aβ+ | t -test | |
Demographics | |||
Sex (male, female) | 28 (15, 13) | 39 (24, 15) | t=1.29, P=0.20 |
Age (s.d.) | 75.61 (5.50) | 73.05 (6.96) | t=1.67, P=0.10 |
Education (s.d.) | 15.39 (3.32) | 16.26 (2.71) | t=1.13, P=0.26 |
Cognitive measure | |||
Logical memory (immediate) | 14.73±0.60 | 7.51±0.43 | t=9.72, P<0.001 |
Logical memory (delayed) | 13.51±0.67 | 4.27±0.52 | t=10.86, P<0.001 |
RAVLT (immediate) | 8.14±0.54 | 3.79±0.40 | t=6.44, P<0.001 |
RAVLT (delayed) | 8.0±0.58 | 2.77±0.45 | t=7.12, P<0.001 |
RAVLT (recall) | 13.05±0.34 | 9.64±0.47 | t=5.88, P<0.001 |
Boston Naming Test | 27.81±0.42 | 26.01±0.84 | t=1.91, P=0.03 |
Semantic Fluency A | 19.45±0.65 | 15.63±0.68 | t=4.05, P<0.001 |
Semantic Fluency V | 14.26±0.61 | 10.57±0.51 | t=4.66, P<0.001 |
CDR | 0.01±0.03 | 0.49±0.01 | t=14.87, P<0.001 |