Figure 5: Global pathways regulation in response to drug treatments. | Nature Communications

Figure 5: Global pathways regulation in response to drug treatments.

From: Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

Figure 5

(a) Heat map of kinase substrate motif enrichment (FDR<0.02) in glucose and drug-induced phosphoproteomes. (b) Phosphoproteomics data were mapped onto a global naive network of signalling information and then filtered (Supplementary Material). Nodes were colour coded according to the class of compounds responsible of their phosphorylation.

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