Figure 5: TSC22D4 levels correlate with insulin sensitivity in humans.
From: Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
(a) Quantitative PCR analysis of Tsc22d4 mRNA expression in livers of patients with type 2 diabetes (T2D, n=26) or normal glucose tolerance (NGT, n=40) Error bars indicate standard error of the mean (s.e.m.). (b) Correlation of hepatic expression of Tsc22d4 mRNA and fasting plasma glucose in the same patients as in a. (c) Correlation of human liver expression of Tsc22d4 mRNA and glucose infusion rate (GIR) during hyperinsulemic-euglycaemic clamp study in the same patients as in a. Statistical analysis for a: Student’s t-test, b and c: Pearson correlation coefficient, *P≤0.05; **P≤0.01; ***P≤0.001.
