Figure 4: The sensitivity of SRS imaging was comparable to EMG for 5-week SOD1G93A versus WT mice.
From: Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
(a–c) Quantitative parameters measured by EMG for 5 weeks SOD1G93A versus WT mice. (d) Quantification of lipid ovoids by SRS imaging for 5 weeks SOD1G93A versus WT mice. (e) Ratio of mice showing qualitative positive sharp waves by EMG for 5-week SOD1G93A versus WT mice. (f) Ratio of mice showing myelin degeneration signs by SRS imaging for 5 weeks SOD1G93A versus WT mice. N=4 for SOD1G93A versus N=6 for WT. Data are presented as mean±s.e.m., and error bars show s.e.m.
