Figure 5: SRS imaging of SOD1G93A under minocycline treatment.
From: Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
(a) Experimental design of long-term serial in vivo SRS imaging for SOD1G93A under minocycline treatment. (b) SOD1G93A versus WT long-term serial in vivo SRS images at 8 weeks postnatal. Scale bar, 50 μm. (c) Quantification of lipid ovoids for long-term serial in vivo SRS imaging throughout disease progression. (d–f) Correlation and regression analysis between SOD1G93A copy number and lipid ovoid deposition at 5 weeks (d), 8 weeks (e) and 11 weeks (f) of postnatal age.
