Figure 3: NE and ACh activity display different time courses around walking.
From: Pupil fluctuations track rapid changes in adrenergic and cholinergic activity in cortex
(a–c) Mean calcium trace for NE axons (a), ACh axons (b) or blebs (c), aligned to the start (left) and end (right) of running. Pupil diameter (grey) and treadmill velocity (dark green) are plotted on the same time base. (d) A large increase in activity during the first second of walking is apparent in NE and ACh axons, but not blebs. During the last second of walking, NE activity has reduced significantly to near baseline, whereas ACh activity remains high. Error bands and bars are a 68% bootstrap confidence interval.
