Figure 2: Co-localization profile of SIX6OS1 with central element proteins.
From: C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility
(a) Double immunostaining of SIX6OS1 (green) and SYCP1, SYCE1, SYCE3, SYCE2 or TEX12 (red). Immunofluorescence signal levels were measured on synapsed chromosome axes. Left plots represent normalized signal intensity profiles of SIX6OS1 with each CE protein. Right plots show regression analysis of the correlation between each pair. (b) Plot of the mean correlation between SIX6OS1 and SYCP1, SYCE1, SYCE3, SYCE2 or TEX12 (n=38 axial elements (AEs), mean±s.d.). The best correlation value was obtained with SYCE1. Scale bar, 2.5 μm.
