Table 3 Statistics and comparison of data in Fig. 4f.

From: BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

GBM01

Mean fork speed (kb per min)

s.d.

s.e.m.

n

pcDNA/shCTRL

0.6914

0.309

0.0138

500

pcDNA/shBRCA1-2

0.4033

0.1829

0.0081

500

pcDNA/shBRCA1-4

0.504

0.2305

0.0131

500

pcDNA-RRM2/shCTRL

0.5268

0.2186

0.0098

500

pcDNA-RRM2/shBRCA1-2

0.7508

0.2781

0.0124

500

pcDNA-RRM2/shBRCA1-4

0.975

0.3334

0.0149

500

  1. Statistical significance was calculated by Student’s t test: pcDNA/shBRCA1-2 versus pcDNA-RRM2/shBRCA1-2 (****P<0.0001); pcDNA/shBRCA1-4 versus pcDNA-RRM2/shBRCA1-4 (****P<0.0001).
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