Figure 2: HATs, GCN5 and Tip60 are required for LTM maintenance. | Nature Communications

Figure 2: HATs, GCN5 and Tip60 are required for LTM maintenance.

From: Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies

Figure 2

(a) Knockdown of GCN5 and Tip60 impairs 4-day LTM maintenance (from left to right, n=10, 10, 11, 11, 8, 7, 8, 8, 11, 12, 8, 9, 8 and 8). (b) Knockdown of GCN5 and Tip60 does not affect LTM formation (from left to right, n=7, 8, 8, 8, 8, 8, 8, 8, 7, 7, 8, 8, 8 and 8). (c) Knockdown of Tip60, but not GCN5, impairs 7-day LTM maintenance. Wild-type flies (+/+) or the flies carrying the indicated UAS transgenes were crossed with MBsw and their progeny were tested as shown (from left to right, n=11, 10, 10, 9, 7 and 8). *P<0.05, **P<0.01 and ***P<0.001 by Student’s t-test.

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