Figure 3: Synthesis of C-terminal hexapeptide 2 using micro-flow amidation.
Conditions: (a) Pd(PPh3)4, PhSiH3, CH2Cl2/MeOH, r.t., 1–1.5 h, batch. (b) PS-Ph3P-Pd, PhSiH3, CH2Cl2/MeOH/H2O, r.t., 1 h, batch.
Figure 3: Synthesis of C-terminal hexapeptide 2 using micro-flow amidation. | Nature Communications
