Figure 5: DNA methylation relates with cell-specific TXK gene expression. | Nature Communications

Figure 5: DNA methylation relates with cell-specific TXK gene expression.

From: Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease

Figure 5

TXK (Tyrosine Kinase) DNA methylation (a) and gene expression (c) in whole blood (Globin mRNA depleted), CD8+ T Cells, CD4+ T Cells and, CD14+ monocytes. Differences in methylation (Diff Beta), and gene expression (LogFC, Log fold change) and uncorrected P values (p) derived from linear models including age and sex as covariates. (b) demonstrates correlation (P Values derive from Pearson’s correlation) between TXK gene expression and DNA methylation in matched samples. Boxplots show the median, 25th and 75th percentiles, and 1.5 * interquartile range (error bars).

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