Table 2 Sequence identity of 3E1 epitope by subtype.

Residue		Consensus ^*	CA04/H1 Sequence	Per cent Identity by Subtype
				H1 (5532) ^†	H5 (217) ^†	H2 (80) ^†	H9 (6) ^†	H13 (93) ^‡	H16 (38) ^‡
HA1	18	H	H	99	100	100	0 (Q)^§	0 (L)^§	0 (L)^§
	38	H	H	99	99	100	100	0 (S)^§	0 (S)^§
	326	T	T	99	100	100	78 (V)^§ 22 (I)	100	100
HA2	16	G	G	99	100	100	100	100	100
	18	V	V	97	100	97	100	98 (I)^§	100 (I)^§
	19	D	D	99	100	100	0 (A)^§	0 (N)^§	0 (N)^§
	20	G	G	100	100	100	100	100	100
	21	W	W	100	100	100	100	100	100
	34	Y	Y	99	100	100	0 (M)^§	26 (I)^§	0 (I)^§
	38	L/K	L	88 (L)^§ 12 (Q)	98 (K)^§	100 (K)^§	100 (R)^§	100 (K)^§	100 (K)^§
	42	Q	Q	100	100	100	100	100.0	100
	45	I	I	99	99	0 (F)^§	78 (I)^§ 22(V)	100	96
	48	I	I	99	0 (V)^§	100	100	100	100
	49	T	T	99	100	100	100	100	100
	52	V	V	99	100	90	100	0 (I)^§	0 (I)^§

^*Most common residue at position by simple majority across all group 1 sequences. HA1 residues are listed first, followed by HA2 residues.
^†Number of sequences available for subtype infecting humans at time of download.
^‡Number of sequences available for subtype at time of download.
^§Most common residue in this subtype.

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