Figure 6: moDCs are found in psoriatic skin. | Nature Communications

Figure 6: moDCs are found in psoriatic skin.

From: Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation

Figure 6

(a) Indirect immunostaining of human psoriatic skin for CD1a and CD14. The dermis and epidermis are demarcated by the white dashed lines. Single-colour images are shown above the merged images. The left and right panels are from different subjects. Magnifications are × 100 for the upper panels and × 200 for the lower panels. (b) Indirect immunostaining of the dermis of human psoriatic skin for HLA-DR and CD14. Single-colour images are shown above the merged images. Lower panels show staining using isotype controls in place of primary antibodies. Magnifications are × 100 for the upper panels, × 200 for the middle panel and × 50 for the lower panels. Nuclei are stained using DAPI. Staining is visualized using pseudocolours as indicated, arrows indicate both single- and double-positive cells, and scale bars are 50 μm. Sections are from two (a), or one subject (b), representative of three subjects.

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