Figure 8: Definition of individualized V gene germline repertoires in the Chinese-origin macaques by IgDiscover. | Nature Communications

Figure 8: Definition of individualized V gene germline repertoires in the Chinese-origin macaques by IgDiscover.

From: Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity

Figure 8

(a) The left phylogenetic tree shows the relationship between the seven VH sequences that constitute the minimum VH database. The right phylogenetic tree illustrates IgDiscover identifying a repertoire of 70 VH alleles in rhesus F132 using a seven sequence minimal VH set as the starting database. The seven individual VH families are colour coded: VH1, pink; VH2, green; VH3, red; VH4, blue; VH5, purple; VH6, orange; and VH7, brown. (b) Total number of alleles and the number of novel VH alleles in each of the five Chinese-origin rhesus macaques analysed in addition to the V kappa and V lambda sequences from three of this group. (c) Venn diagram showing the comparison of VH allelic diversity within the group of five rhesus macaques. (d) Venn diagram showing the comparison of VK allelic diversity within the group of three rhesus macaques. (e) Venn diagram showing the comparison of VL allelic diversity within the group of three rhesus macaques.

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