Table 2 IgDiscover output of 5′UTR and Leader sequence from VH1 family alleles.

From: Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity

  1. *Reaction conditions:1/LiHMDS/2/[Pd(η3-C3H5)Cl]2/S-IPr·HCl=200/200/100/2.5/5; 0.1 M of ketone 1; T=30oC; B/L and dr was determined by 1H NMR, dr is the ratio of (±)-(syn,anti)-3/other diastereoisomers; Isolated yield. †T=50 oC. Solvent=THF. §OBoc of 2 was replaced with OP(OEt)2. ||The yield was determined by 1H NMR.
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