Figure 4: Subcortical brain structures and the derivation of shape measures.
From: Heritability of the shape of subcortical brain structures in the general population

Overview of the subcortical brain structures studied in this manuscript and the derivation of the shape measures. (a) The seven structures with corresponding number of vertices: accumbens, amygdala, caudate, hippocampus, pallidum, putamen and thalamus. (b,c) The two vertex-wise measures of shape: the radial distance is defined as the distance of a vertex to the medial curve of the structure, for example, the hippocampus in b. The Jacobian determinant captures the deformation that is needed to map a subject-specific shape to a template, which is shown with an example of the accumbens in c.