Figure 2: Superimposed structures of the four hTrxR–hTrx complexes. | Nature Communications

Figure 2: Superimposed structures of the four hTrxR–hTrx complexes.

From: Crystal structure of the human thioredoxin reductase–thioredoxin complex

Figure 2

We used a ribbon representation to show the different positions of the Trx molecules in the four complexes (orthorhombic: grey and cyan; monoclinic: blue and red). There are only slight differences around the intra-molecular disulphide between U498C′hTrxR1 and C32hTrx1 but for example in the regions around K82 and around A18 the distance between Cα-atoms increases up to 4 Å.

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