Figure 3: Overview of the hTrxR1 dimer with bound hTrx1.
From: Crystal structure of the human thioredoxin reductase–thioredoxin complex
hTrxR1 (grey) and hTrx1 (blue) are shown in ribbon representation. FAD (yellow) and the N-terminal redox centre (red) are shown in ball representation. The different conformations of the C-terminus (last 8 residues) as found in the 'oxidized waiting position', 'reduced waiting position', and in the hTrxR1–hTrx1 complex are coloured magenta, orange, and green, respectively. Molecular graphics images were produced using the UCSF Chimera package40.
