Figure 3: General phenotype of KO mice.
From: Armc5 deletion causes developmental defects and compromises T-cell immune responses
(a) Representative photos of WT, HT, KO fetuses on embryonic day 14. (b) Representative photos of adult KO and WT littermates. Left panel: males (8 weeks old); right panel: females (12 weeks old). (c) Body weight (means±s.e.m.) of Armc5 KO and WT littermates at age 4 and 8 weeks. Mouse numbers (n) per group are indicated. *p<0.001 (two-tailed Student’s t-test). (d) Morphology (upper panel) and histology (lower panel, HE staining) of adrenal glands from old KO mice (19 months old). Magnification: × 5. Scale bar: 500 μm. (e) Serum glucocorticoid levels in old KO mice. Means±s.e.m. of serum glucocorticoids in old KO and WT mice are shown. Age of each group (means±s.e.m.) and mouse number per group are indicated. Two-tailed Student’s t-test was used for statistical analysis.
