Figure 9: T-cell cytokine production and virus titres in KO mice after LCMV infection.
From: Armc5 deletion causes developmental defects and compromises T-cell immune responses
(a) Absolute number of virus-specific, cytokine-producing CD8 cells. (b,c) Percentages of virus-specific, cytokine-producing cells among CD8 cells (b) and CD4 cells (c) on day 8 post LCMV infection. Means±s.e.m. of data are shown. Mouse numbers (n) per group and P values (two-tailed Student's t-test) are indicated. (d) Means±s.e.m. of percentages of gp33–41-specific CD107a+GranB+ CD8 T cells on day 8 post LCMV infection. Mouse numbers (n) per group and P values (two-tailed Student's t-test) are indicated. (e) Means±s.e.m. of viral titres in the kidney, liver and spleen on day 8 post LCMV infection. Mouse numbers (n) per group and P values (two-tailed Student's t-test) are indicated.
