Nature Communications 7: Article number: 12984 (2016); Published: 30 September 2016; Updated: 15 December 2016

Two previous studies describing the effects of autoinducer 2 (AI-2) on biofilm formation and chemotaxis in Escherichia coli were inadvertently omitted from the reference list of this Article. A reference to these studies along with ref. 27 should have been provided in the Introduction, as follows: ‘It has been previously reported that, in E. coli, AI-2 can modulate biofilm formation (González-Barrios et al. 2006) and virulence-related phenotypes such as chemotaxis, swimming motility and attachment to host cells in vitro (Bansal et al. 2008, ref. 27).’ These findings should have also been mentioned in the Abstract, where the physiological role of AI-2 in E. coli and other bacteria is referred to, and in the sections discussing motility, chemotaxis and biofilm formation in E. coli.

González Barrios, A. F. et al. Autoinducer 2 controls biofilm formation in Escherichia coli through a novel motility quorum-sensing regulator (MqsR, B3022). J. Bacteriol. 188, 305-316 (2006).

Bansal, T., Jesudhasan, P., Pillai, S., Wood, T. K. & Jayaraman, A. Temporal regulation of enterohemorrhagic Escherichia coli virulence mediated by autoinducer-2. Appl. Microbiol. Biotechnol. 78, 811-819 (2008).