Figure 5: Reduced JAK1 and STAT1 phosphorylation in patient’s fibroblasts at different time points after IFN-α and IFN-γ stimulation. | Nature Communications

Figure 5: Reduced JAK1 and STAT1 phosphorylation in patient’s fibroblasts at different time points after IFN-α and IFN-γ stimulation.

From: Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection

Figure 5

(a,b) Primary fibroblasts from the patient or a healthy control were treated with the IFN-α (a) or IFN-γ (b) for indicated times and protein extracts were subjected to immunoblotting. Representative of two independent experiments. Fold change of band densitometry is indicated (number below bands and bar graphs in Supplementary Fig. 7).

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