Table 1 Biometric and echocardiographic parameters of wild-type (WT) and Md2−/− (KO) mice fed control or high-fat diet for 4 months.

From: Saturated palmitic acid induces myocardial inflammatory injuries through direct binding to TLR4 accessory protein MD2

Parameter

B6-Con (N=8)

B6-HFD (N=8)

KO-Con (N=8)

KO-HFD (N=8)

Heart rate (bmp)

469.8±34.76

492.4±20.8

445.6±25.85

460.0±46.50

Fractional shortening (%)

41.92±0.75

38.13±1.34*

43.30±1.02

40.18±0.82#

LVEF (%)

79.38±0.79

67.98±1.21*

78.10±1.52

77.62±1.10#

LVID d (mm)

3.02±0.05

3.37±0.06*

3.22±0.06

3.38±0.08

LVID s (mm)

1.78±0.05

2.21±0.06*

1.85±0.08

1.88±0.05#

LVPW d (mm)

0.91±0.005

0.96±0.004

0.88±0.010

0.91±0.008

LVPW s (mm)

1.02±0.007

1.15±0.02*

1.04±0.01

1.05±0.01#

LVFW d (mm)

0.91±0.01

0.97±0.007*

0.90±0.01

0.91±0.01#

LVFW s (mm)

1.08±0.005

1.15±0.013*

1.03±0.014

1.07±0.016#

IVS d (mm)

0.92±0.013

0.95±0.006

0.88±0.008

0.90±0.013#

IVS s (mm)

1.07±0.003

1.16±0.016*

1.03±0.012

1.04±0.024#

  1. ANOVA, analysis of variance; HFD, high-fat diet; IVS, interventricular septum; d, diastolic; KO, knockdout; LFFW, left ventricle free wall; LVEF, left ventricle ejection fraction; LVID, left ventricle internal dimension; LVPW, left ventricle posterior wall; s, systolic.
  2. Data are reported as mean±s.e. and analysed by one-way ANOVA, *P<0.05 versus B6-LF group; #P<0.05 versus B6-HFD group.